I would like to combine the % of overlapping regions retrieved from EpiExplorer and the
statistical significance found with Genomic HyperBrowser. However, the HyperBrowser does not give the % of overlaps of the control regions (random regions that are generated to calculate the null distribution). EpiExplorer gives this %, but I couldn't find how are the control regions calculated. From the region lengths plots I can see that the control regions have the same length distribution as my data, but what about the gaps between regions? Are these preserved as well? Then I would know which 'preservation rule' to pick in the HyperBrowser so that it would randomize the positions in the same way.
Hi!
I would like to combine the % of overlapping regions retrieved from EpiExplorer and the statistical significance found with Genomic HyperBrowser. However, the HyperBrowser does not give the % of overlaps of the control regions (random regions that are generated to calculate the null distribution). EpiExplorer gives this %, but I couldn't find how are the control regions calculated. From the region lengths plots I can see that the control regions have the same length distribution as my data, but what about the gaps between regions? Are these preserved as well? Then I would know which 'preservation rule' to pick in the HyperBrowser so that it would randomize the positions in the same way.
Best regards,
Mario